Study of thyroid function Abnormalities in newly diagnosed HIV infected patients

Background

There has been a significant increase in number of HIV patients in India . Endocrinal involvement is common in these patients especially involvement of thyroid in the form of subclinical hypothyroidism which are related to severity of HIV infection, nutritional status and HAART in various studies. There is little data on abnormalities of thyroid function tests in newly diagnosed HIV patients and only few studies undertaken in India and hence this study is done

Objective

(1) To study thyroid function abnormalities in newly diagnosed HIV patients.

(2) To find out relation between thyroid function abnormalities and severity of illness in HIV infected patients,.

METHODS Fifty patients who are diagnosed to have HIV infection according to National AIDS Control Organisation (NACO) March 2007, who fulfill inclusion and exclusion criteria who get admitted to coimbatore medical college hospital from september 2013 to february 2014. Data to be collected by using pre-tested proforma meeting the objectives of the study. All enrolled patients were investigated for thyroid dysfunction by measuring total T3, total T4, TSH .Thyroid function abnormalities were compared with HIV status, CD4 count and WHO clinical stage of HIV disease

Inclusion criteria: newly diagnosed HIV patients in the age group of 20 to 60 years

Exclusion criteria:
1. patients already on Thyroxin treatment.
2. patients on drugs altering thyroid function .
3. Patients who had thyroid surgery in the past.
4. pregnant patients.
5. patients on oral contraceptive pills